Hims & Hers Health Inc. became North America’s fastest-growing online retailer in 2024, and its annual web sales proved strong enough in 2025 to move into yet another distinction: one of the top five online retailers overall in the Health & Beauty category for Digital Commerce 360’s Top 2000 Database.
The new rankings by merchandise category appear as of today in Digital Commerce 360’s new 2026 State of American Ecommerce Report, which contains key takeaways from 2025 ecommerce activity, along with U.S.-based ecommerce projections for 2026. The Top 2000 ranks the most successful online retailers in North America by annual web sales. Among them, 1,857 are based in the U.S.
Thanks to $2.35 billion in ecommerce sales in 2025, Hims & Hers’ rise in Health & Beauty places it among long-established names in Health & Beauty, such as Walgreens Boots Alliance Inc. (No. 1 in the category), iHerb Inc. and Ulta Beauty. Along the way, the company also reached a new deal with the pharmaceutical company Novo Nordisk that will have implications for the role its weight loss offerings play in revenue for the year ahead.
How Hims & Hers became one of the top online retailers in Health & Beauty
Hims & Hers, which got its start in 2017, entered the top five rankings among leading online retailers in the Health & Beauty category this year by outperforming The Estée Lauder Companies, which claimed the No. 5 spot a year earlier.
The Health & Beauty category in the Top 2000 is led by Walgreens Boots Alliance at No. 1, followed by iHerb, Amway and Ulta Beauty.
In addition to being ranked No. 5 in this category, Hims & Hers ranks No. 68 among all online retailers in the Top 2000. That resulted from a culmination of efforts across the products that it sells through its platform.
The company’s ecommerce sales increased by 63.19% year over year in 2025. That followed 70.7% growth in 2024, according to Digital Commerce 360 analysis.
Hims & Hers web sales by year
Nevertheless, the online health care company entered 2026 on a note of uncertainty, thanks to a legal dispute with Novo Nordisk.
GLP-1 products on Hims & Hers
Almost a year ago, Hims & Hers appeared ready to work directly with Novo Nordisk to sell its products. However, tensions proved to be too strong over competing products in the glucagon-like peptide-1 (GLP-1) family of treatments that were being sold through Hims & Hers’ platform.
The companies remained at odds for most of 2025, leading up to Novo Nordisk’s announcement in February 2026 that it would sue Hims & Hers, seeking to stop the sales of competitors to its Wegovy offerings. Novo Nordisk launched the renewed legal offensive despite Hims & Hers announcing on Feb. 7 that it would drop its new pill under threat of a potential investigation by the U.S. Department of Justice.
A resolution finally came on March 9, when both companies announced that Novo Nordisk would drop the lawsuit. In addition, Hims & Hers agreed to end its existing promotions for compounded GLP-1 offerings. In turn, revealed plans to add Novo Nordisk’s Ozempic injections and Wegovy pills and injections to the Hims & Hers platform.
“We see tremendous growth opportunities in the U.S. with the expanding assortment of branded GLP-1 medications,” said Andrew Dudum, co-founder and CEO of Hims & Hers, when the agreement was announced. “I’m excited to have a great partner in Novo Nordisk as we work to create a new model that works for everyday people. This collaboration reflects what’s possible globally when drugmakers, biotech companies, and diagnostic leaders partner with consumer platforms to support scaled distribution of their latest medical innovations.”
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